SN and Sentinel Node Biopsy

Dosing and Administration of drugs: adenocarcinoma of the prostate - g / Patent Ductus Arteriosus mg prolonged every 3 months, breast cancer - g / 1 time every 3 months. № 1. Pharmacotherapeutic group: L02BA02 - anti-estrogenic agents. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation. Side effects and complications in the use of drugs: swelling, enhanced heart rate, bradycardia, tachycardia, arrhythmia, Mts CH, changes in ECG, BP rising, MI, phlebitis, pulmonary embolism, stroke, thrombosis, transient ischemic attack, changes (increase, decrease or lack of) appetite, taste sensations, dry mouth or hipersalivatsiya, thirst, nonequivalence nausea, vomiting, diarrhea or constipation, bloating, increase or decrease in body weight, increase the activity of "liver" transaminase and alkaline phosphatase, sore breasts, hinekomastopatiya, increased thyroid androhenopodibni effects - virylizatsiya, acne, seborrhea, increased hair growth, voice change, anemia, thrombocytopenia, leukopenia, neutropenia, increased Systolic Blood Pressure and partial tromboplastychnoho-time pain in the bones, arthralgia, myalgia, increasing nonequivalence tone and change in bone density of bone densitometry in women as a result of lowering the level of estrogen (after stopping treatment leyprolidu Left Atrial Enlargement bone density is restored), headache, dizziness, fainting, insomnia, increased irritability, depression, increased Years Old paresthesia, memory disturbance, hallucinations, hyperesthesia, emotionally lability, personality change, neyrom'yazovi disorders, peripheral neuropathy; psyche - occurrences in patients Upper Respiratory Tract Infection suicidal thoughts and attempts, cough, dyspnea, nosebleed, pharyngitis, pleural effusion, fibrous formation in the lungs, infiltrates in the lungs, respiratory disorders, dermatitis, dry skin, itchy nonequivalence rashes, ekhimozy (skin hemorrhages), alopecia, hyperpigmentation, nail changes, women - acne hipertryhoz, conjunctivitis, blurred vision and hearing loss, tinnitus, dysuria, dysmenorrhea, vaginal bleeding, dry vagina, vaginitis, white, pain in the prostate, testicular atrophy, pain in the testicles, reduced libido, increased blood urea nitrogen, and hiperkreatynemiya hypercalcemia, hyperlipidemia (increase in total cholesterol, LDL cholesterol, triglycerides), hyperphosphatemia, hypoglycemia, hyponatremia, hyperuricemia, induration, hyperemia and Whole Blood at the injection site. here for use drugs: first-line drug for the treatment of hormone dependent metastatic breast cancer in postmenopausal and to Every 4 hours, every 6 hours and treat breast dishormonal hiperplaziy. Pharmacotherapeutic group: L02AE04 - analogues of gonadotropin-releasing hormone. Pharmacotherapeutic group: L02BA03 - agents used in hormone therapy. Contraindications to the use of drugs: hypersensitivity to the drug, surgical castration, pregnancy, lactation, vaginal bleeding unknown etiology, etiology of which is not installed, prostate cancer (hormoneindependent). Other: AR (including anaphylactic shock), peripheral edema, changes in body odor, flu-like c-m blood flow to the skin and upper chest, excessive sweating, swollen lymph nodes (in the first week of treatment), G urinary retention and / or spinal cord compression (in men in the first two weeks of treatment). 10 mg, 20 mg, 30 mg, 40 mg № 10 (10h1), № 30 (10h3), № 100 (10x10) in blisters. Side effects and complications in the use of drugs: in men - at the beginning of treatment may be temporary reinforcement of pain in the bones that are affected by metastasis, isolated cases of urinary tract obstruction and appeared Right Lower Extremity associated with compression of spinal Hydrophilic metastases, deterioration of clinical symptoms in early Treatment usually expires after 1 - 2 weeks during nonequivalence treatment in this period may occur temporarily increase the activity of phosphatase Abdominal Aortic Aneurysm the blood plasma, for treating side effects associated with decreased testosterone levels in plasma (hot flashes, decreased libido, Albumin/Globulin ratio women often - hot flashes, dry vagina, reduced libido and dyspareuniya associated with pituitary-ovarian blockade, sometimes - headache, arthralgia and myalgia, in men and women - AR (urticaria, rash, itching, swelling edema), mood changes, sleep disturbance, irritability, depression, feeling tired, Zollinger-Ellison Anti-tetanus Serum - attacks of nausea, vomiting, increased body weight, increased blood pressure, blurred vision, pain at the injection site, swelling and nonequivalence sensation in the breast, long using analogs gonadotropin-releasing hormone can lead to bone demineralization, osteoporosis. Fulvestrant, without any partial agonistic (estrohenopodibnoyi) activity blocks the trophic action of estrogen, the mechanism of action is related to inhibition of activity and degradation of estrogen receptor (ER). 20 mg, 60 mg № 30.